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  1. Multifocal occurrence of gastric carcinoma in patients with a family history of gastric carcinoma.

    Article - En anglais


    Smoking and alcoholic beverage drinking habits as well as a family history of cancer are well known risk factors for the multifocal occurrence of squamous cell carcinoma of the esophagus and the head and neck region.

    However, the role of these risk factors in multiple gastric carcinoma remains to be clarified.

    The purpose of this study was to examine the risk factors for multiple gastric carcinoma.


    The smoking and drinking habits as well as the family history of 157 patients with synchronous multiple gastric carcinoma and 157 patients with solitary gastric carcinoma who were similar with regard to gender, age, stage of the tumor, and year of admission were investigated.

    The risk of a multiple occurrence of gastric carcinoma also was elevated using the odds ratio (OR), RESULTS.

    The ORs of a multifocal occurrence of gastric carcinoma in patients who currently smoked and drank alcoholic beverages were 1.1 and 0.8, respectively, although the ORs were not related to the quantity of smoking or drinking.

    In patients with a close relative with gastric carcinoma the OR was 2.1 (95% confidence interval [CI], 1.3-3.7).

    In those patients with =2 close relatives with gastric carcinoma, the OR increased to 5.1 (95% CI, 1.2-21.1).

    Conversely, no significant elevation in the ORs was recognized regarding a family history of other cancers. (...)

    Mots-clés Pascal : Carcinome, Estomac, Facteur risque, Tabagisme, Boisson alcoolisée, Ethanol, Antécédent, Histoire familiale, Epidémiologie, Japon, Asie, Homme, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Carcinoma, Stomach, Risk factor, Tobacco smoking, Alcoholic beverage, Ethanol, Antecedent, Family story, Epidemiology, Japan, Asia, Human, Malignant tumor, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0457844

    Code Inist : 002B13B01. Création : 25/01/1999.