To the authors'knowledge, attributable fractions for cardiac malformations have not been reported before.
The Baltimore-Washington Infant Study published factors associated with several major cardiac malformations in Maryland, the District of Columbia, and adjacent counties of northern Virginia in 1981-1989.
For eight of these malformations, the authors provide attributable fractions of those factors that are potentially causal. attributable fractions range from 13.6% (four factors) for hypoplastic left heart to 30.2% (seven factors) for transposition of great arteries with intact ventricular septum.
Extra attributable fraction for factor alpha, defined as summary attributable fraction for all factors minus that for all but alpha, is largest for : 1) patemal marijuana use in transposition of great arteries with intact ventricular septum, 7.8% ; 2) patemal anesthesia in tetralogy of Fallot, 3.6% ; 3) painting in atrioventricular septal defect with Down syndrome, 5.1% ; 4) solvent/degreasing agent exposure in hypoplastic left heart, 4.6% ; 5) sympathomimetics in coarctation of aorta, 5.8% ; 6) pesticide exposure in isolated membranous ventricular septal defect, 5.5% ; 7) hair dye in multiple/multiplex membranous ventricular septal defect, 3.3% ; and 8) urinary tract infection in atrial septal defect, 6.4%. Percent-of-cases-exposed dominates relative risk in attributable fraction. (...)
Mots-clés Pascal : Maladie congénitale, Malformation, Cardiopathie, Epidémiologie, Facteur risque, Etiologie, Nourrisson, Homme, Analyse statistique, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie, Risque attribuable
Mots-clés Pascal anglais : Congenital disease, Malformation, Heart disease, Epidemiology, Risk factor, Etiology, Infant, Human, Statistical analysis, United States, North America, America, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0453634
Code Inist : 002B12A08. Création : 25/01/1999.