Study objective-This study examined the impact on children's respiratory health of a government air quality intervention that restricted the sulphur content of fuels to 0.5% from July 1990 onwards.
Design/setting/participants-This study examined the changes, one and two years after the introduction of the intervention, in airway hyperreactivity of non-asthmatic and non-wheezing, primary 4,5, and 6, school children aged 9-12 years living in a polluted district compared with those in a less polluted district.
Bronchial hyperreactivity (BHR) (a 20% decrease in FEV, provoked by a cumulative dose of histamine less than 7.8 mumol) and bronchial reactivity slope (BR slope) (percentage change in logarithmic scale in FEV1 per unit dose of histamine) were used to estimate responses to a histamine challenge.
The between districts differences after the intervention were studied to assess the effectiveness of the intervention.
Main results-In cohorts, comparing measurements made before the intervention and one year afterwards, both BHR and BR slope declined from 29% to 16% (p=0.026) and from 48 to 39 (p=0.075) respectively in the polluted district ; and from 21% to 10% (p=0.001) and 42 to 36 (p>0.100) in the less polluted district.
Comparing measurements made in 1991 (one year after intervention) with those in 1992 (two years after intervention), only the polluted district showed a significant decline from 28% to 12% (p=0.016) and from 46 to 35 (p=0. (...)
Mots-clés Pascal : Asthme, Bronche pathologie, Pollution air, Toxicité, Epidémiologie, Facteur risque, Enfant, Homme, Milieu scolaire, Ecole primaire, Hong Kong, Chine, Asie, Etude comparative, Variation géographique, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Santé et environnement
Mots-clés Pascal anglais : Asthma, Bronchus disease, Air pollution, Toxicity, Epidemiology, Risk factor, Child, Human, School environment, Primary school, Hong Kong, China, Asia, Comparative study, Geographical variation, Respiratory disease, Obstructive pulmonary disease, Health and environment
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0453606
Code Inist : 002B30A02A. Création : 25/01/1999.