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  1. Differences in risk factors for being either a hepatitis B carrier or anti-hepatitis C+in a hepatoma-hyperendemic area in rural Taiwan.

    Article - En anglais

    This is a study of the differences in the risk factors for being either hepatitis B surface antigen positive [HBsAg (+) ] or antibody to hepatitis C virus positive [Anti-HCV (+) ] in A-Lein, a rural area in southern Taiwan, an area which also has a high hepatoma mortality rate.

    Three hundred eighty-five patients age =40 years participated in hepatoma screening at the A-Lein Community Health Center during 1995.

    Those who were HBsAg (-) and anti-HCV (-) or had coinfection of HBsAg (+) and anti-HCV (+) were excluded, leaving 293 patients : 109 HBsAg (+) and 184 anti-HCV (+). The anti-HCV (+) patients had a lower socioeconomic status (as defined by level of education and type of occupation) and were older than HBsAg (+) patients (P<0.05).

    Those with higher alanine aminotransferase levels (ALT) also had a higher anti-HCV (+) to HBsAg (+) odds ratio (OR), and a dose response relationship was found, P<0.0001.

    Anti-HCV (+) patients were more likely than HBsAg (+) patients to have a spouse who shared the infection, OR=5.11 ; 95% Cl, 2.30-11.28.

    Anti-HCV (+) patients were more likely than HBsAg (+) patients to have had blood transfusions (OR=2.66 ; 95% Cl, 1.20-5.89), frequent medical injections (OR=2.64 ; 95% Cl, 1.62-4.31), or injections by non-licensed medical providers (OR=1.91 ; 95% Cl, 1.18-3.09).

    Multiple logistic regression analysis showed that the significant factors for anti-HCV (+) patients vs.

    HBsAg (+) patients are drinking habit (OR=3.45 ; 95% Cl, 1.02-11. (...)

    Mots-clés Pascal : Hépatite virale C, Virose, Infection, Hépatite virale B, Injection, Voie intraveineuse, Epidémiologie, Facteur risque, Homme, Taiwan, Asie, Zone rurale, Etude comparative, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Viral hepatitis B, Injection, Intravenous administration, Epidemiology, Risk factor, Human, Taiwan, Asia, Rural area, Comparative study, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0453189

    Code Inist : 002B05C02G. Création : 25/01/1999.