A large introductory study of Cyclofem, a once-a-month injectable contraceptive, was conducted in three Mexican provinces.
A total of 3457 healthy women participated : 640 women from rural areas (community-based component) and 2817 women from urban and suburban areas (health center-based component).
A total of 20,316 women-months of treatment experience were accumulated during a one year period.
Cyclofem proved its use-effectiveness (pregnancy rate of 0.03%) and its safety under routine service conditions of family planning facilities in Mexico.
The overall life table continuation rate at 1 year was 26.1%. Higher continuation rates were observed in the community-based component (36.6%) as compared to the health center component (23. 7%). The most common reason for method discontinuation was change of address.
Only 15% of the discontinuations were attributable to the injectable contraceptive method, with the overall 1 year discontinuation rate for bleeding problems (including amenorrhea) was<11%. These observations underscore the importance of appropriate counseling and follow-up measures, providing convenient access to repeat injections, and other service delivery issues related to continuation of Cyclofem.
The results of this trial have once again demonstrated that Cyclofem is a highly effective method with an acceptable side effect profile. (...)
Mots-clés Pascal : Médroxyprogestérone, Oestrogène, Progestatif, Oestroprogestatif, Contraceptif, Forme libération contrôlée, Voie intramusculaire, Mensuel, Suspension, Contraception, Homme, Femelle, Mexique, Amérique Centrale, Amérique, Epidémiologie, Planning familial, Facteur sociodémographique, Cipionate d'estradiol, Méthode combinée
Mots-clés Pascal anglais : Medroxyprogesterone, Estrogen, Progestagen, Estroprogestagen, Contraceptive, Controlled release form, Intramuscular administration, Monthly, Suspension, Contraception, Human, Female, Mexico, Central America, America, Epidemiology, Family planning, Sociodemographic factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0452407
Code Inist : 002B20A01. Création : 25/01/1999.