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  1. Introduction of Cyclofem once-a-month injectable contraceptive in Mexico.

    Article - En anglais

    A large introductory study of Cyclofem, a once-a-month injectable contraceptive, was conducted in three Mexican provinces.

    A total of 3457 healthy women participated : 640 women from rural areas (community-based component) and 2817 women from urban and suburban areas (health center-based component).

    A total of 20,316 women-months of treatment experience were accumulated during a one year period.

    Cyclofem proved its use-effectiveness (pregnancy rate of 0.03%) and its safety under routine service conditions of family planning facilities in Mexico.

    The overall life table continuation rate at 1 year was 26.1%. Higher continuation rates were observed in the community-based component (36.6%) as compared to the health center component (23. 7%). The most common reason for method discontinuation was change of address.

    Only 15% of the discontinuations were attributable to the injectable contraceptive method, with the overall 1 year discontinuation rate for bleeding problems (including amenorrhea) was<11%. These observations underscore the importance of appropriate counseling and follow-up measures, providing convenient access to repeat injections, and other service delivery issues related to continuation of Cyclofem.

    The results of this trial have once again demonstrated that Cyclofem is a highly effective method with an acceptable side effect profile. (...)

    Mots-clés Pascal : Médroxyprogestérone, Oestrogène, Progestatif, Oestroprogestatif, Contraceptif, Forme libération contrôlée, Voie intramusculaire, Mensuel, Suspension, Contraception, Homme, Femelle, Mexique, Amérique Centrale, Amérique, Epidémiologie, Planning familial, Facteur sociodémographique, Cipionate d'estradiol, Méthode combinée

    Mots-clés Pascal anglais : Medroxyprogesterone, Estrogen, Progestagen, Estroprogestagen, Contraceptive, Controlled release form, Intramuscular administration, Monthly, Suspension, Contraception, Human, Female, Mexico, Central America, America, Epidemiology, Family planning, Sociodemographic factor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0452407

    Code Inist : 002B20A01. Création : 25/01/1999.