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  1. Lifetime panic-depression comorbidity in the National Comorbidity Survey.

    Article - En anglais


    The National Comorbidity Survey is a nationally representative survey of the prevalences and correlates of DSM-III-R disorders in the US household population.


    Retrospective age-at-onset reports were used to study predictive relationships between lifetime panic and depression.


    Strong associations were found between the lifetime prevalences of panic and major depressive episodes (odds ratios : for panic attacks with depression, 6.2 ; for panic disorder with depression, 6.8).

    These associations were not significantly influenced by the inclusion or exclusion of respondents with mania.

    Temporally primary depression predicted a first onset of subsequent panic attacks but not of panic disorder.

    Temporally primary panic attacks, with or without panic disorder and whether or not the panic was persistent, predicted a first onset of subsequent major depression.

    The associations between panic attack and depression were attenuated in models that controlled for prior traumatic life experiences and histories of other DSM-III-R disorders.


    Lifetime panic-depression comorbidity characterizes most community respondents with panic disorder and a substantial few of those with major depression.

    The absence of a dose-response relationship suggests that primary panic attack is a marker, rather than a causal risk factor, of subsequent depression.

    Primary depression, in comparison, appears to be a genuine risk factor for secondary panic attacks. (...)

    Mots-clés Pascal : Panique, Association morbide, Etat dépressif, Prévalence, Epidémiologie, Santé mentale, Etats Unis, Amérique du Nord, Amérique, Homme, Trouble anxieux, Trouble humeur

    Mots-clés Pascal anglais : Panic, Concomitant disease, Depression, Prevalence, Epidemiology, Mental health, United States, North America, America, Human, Anxiety disorder, Mood disorder

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0449339

    Code Inist : 002B18C08A. Création : 25/01/1999.