Occupational exposure to natural rubber latex has led to sensitization of health-care workers.
However, the prevalence of latex allergy among occupationally exposed workers in American hospitals has not been reproducibly determined.
The objectives of the current study were to determine the prevalence of and risk factors for latex sensitization among a cohort of highly exposed healthcare workers.
Participants were 168 of 171 eligible anesthesiologists and nurse anesthetists working in the Department of Anesthesiology and Critical Care Medicine.
A clinical questionnaire was administered, and testing was performed using a characterized nonammoniated latex reagent for puncture skin testing, a Food and Drug Administration-approved assay to quantify latex-specific immunoglobulin E antibody in serum, and, when required for clarification, a validated two-stage (contact-inhalation) latex glove provocation procedure.
The prevalence of latex allergy with clinical symptoms and latex sensitization without clinical symptoms was 2.4% and 10.1%, respectively.
The prevalence of irritant or contact dermatitis was 24%. The risk factors identified for latex sensitization were atopy (odds ratio, 14.1 ; 95% CI, 1.8-112.1 ; P=0.012) ; history of allergy to selected fruits, such as bananas, avocados, or kiwis (odds ratio, 9.8 ; 95% CI, 1.6-61.9 ; P=0.015) ; and history of skin symptoms with latex glove use (odds ratio, 4.6 ; 95% CI, 1.6-13.4 ; P=0.006). (...)
Mots-clés Pascal : Latex, Allergie, Toxicité, Exposition professionnelle, Anesthésiste, Homme, Personnel sanitaire, Hôpital, Epidémiologie, Facteur risque, Prévalence, Médecine travail, Etats Unis, Amérique du Nord, Amérique, Immunopathologie, Gant
Mots-clés Pascal anglais : Latex, Allergy, Toxicity, Occupational exposure, Anesthesiologist, Human, Health staff, Hospital, Epidemiology, Risk factor, Prevalence, Occupational medicine, United States, North America, America, Immunopathology, Glove
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0445105
Code Inist : 002B03L06. Création : 25/01/1999.