logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Smoking history, alcohol consumption, and systemic lupus erythematosus : a case-control study.

    Article - En anglais

    Objective

    To investigate the effect of smoking on the development of systemic lupus erythematosus (SLE), and the association between alcohol consumption and the disease.

    Methods-450 subjects (150 SLE patients and 300 controls) from Nottingham, UK were interviewed in a case-control study.

    Controls were matched to cases for age and sex.

    All patients met at least four of the American Rheumatology Association criteria for SLE.

    Controls were randomly selected from the Nottingham Family Health Services Authority register.

    Information was collected by interview administered questionnaire concerning demographic variables, smoking histories, and drinking habits.

    Results

    Analysis of the data by conditional logistic regression revealed current smokers to have a significantly increased risk of development of SLE compared with never smokers (odds ratio (OR) 1.95,95% confidence intervals (CI) 1.14,3.31), although ex-smokers were not at increased risk.

    There was also suggestion of a marked, highly significant negative association between SLE and alcohol consumption, the magnitude of which increased with units consumed.

    Conclusions-This study suggests that current smokers are at increased risk of developing SLE compared with non-smokers and ex-smokers.

    In contrast, alcohol consumption seems to be negatively associated with the disease.

    Mots-clés Pascal : Lupus érythémateux, Disséminé, Facteur risque, Cigarette, Alcool, Consommation, Analyse corrélation, Symptomatologie, Homme, Epidémiologie, Royaume Uni, Europe, Etude cas témoin, Questionnaire, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie, Facteur socioculturel

    Mots-clés Pascal anglais : Lupus erythematosus, Disseminated, Risk factor, Cigarette, Alcohol, Consumption, Correlation analysis, Symptomatology, Human, Epidemiology, United Kingdom, Europe, Case control study, Questionnaire, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0432827

    Code Inist : 002B07. Création : 25/01/1999.