Data from the 1988 National Maternal and Infant Health Survey were used to examine whether regular use of multivitamin/mineral supplements could modify the relation between maternal smoking and fetal death.
Maternal smoking was defined as the self-reported average number of cigarettes smoked after recognition of pregnancy.
Regular supplement use was defined as use of multivitamin/mineral supplements for at least 3 days per week during the 3 months before and/or after recognition of pregnancy.
The sample comprises 12,465 singleton pregnancies, including 9,402 livebirths and 3,063 fetal deaths.
Odds ratios were derived from logistic regression analyses after adjustment for a number of demographic and reproductive variables.
Major findings are that 1) smoking increased the risk of fetal death ; 2) regular supplement use either before or after recognition of pregnancy did not affect the risk of fetal death in the absence of matemal smoking ; 3) odds ratios for fetal death among smoking women who regularly used supplements were generally smaller than those for women who did not regularly use supplements but who smoked a comparable number of cigarettes ; and 4) a significant negative excess risk due to interaction was observed among women who regularly used supplements before recognition of pregnancy and smoked 20 or more cigarettes a day. (...)
Mots-clés Pascal : Tabagisme, Mère, Supplémentation, Vitamine, Minéral, Mort, Gestation, Epidémiologie, Facteur risque, Activité biologique, Foetus, Etats Unis, Amérique du Nord, Amérique, Foetus pathologie, Gestation pathologie
Mots-clés Pascal anglais : Tobacco smoking, Mother, Supplementation, Vitamin, Minerals, Death, Pregnancy, Epidemiology, Risk factor, Biological activity, Fetus, United States, North America, America, Fetal diseases, Pregnancy disorders
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0427015
Code Inist : 002B20F01. Création : 25/01/1999.