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  1. Fulltext. Serum cotinine concentration and self-reported smoking during pregnancy.

    Article - En anglais


    Although during pregnancy there is a better correlation between maternal serum cotinine concentration and adverse outcome than between self-reported smoking and such an outcome, few studies of pregnancy have measured cotinine concentration to determine how much a woman smokes.

    This study assessed the accuracy of self-reported smoking during pregnancy by performing serum cotinine assays on 448 women registered in the Collaborative Perinatal Project (1959-1966).

    Based on the assumption that a serum cotinine concentration of>10 ng/ml represented active smoking, 94.9% of women who denied smoking and 87.0% of women who stated that they smoked (kappa=0.83) reported their status accurately.

    Among smokers, the correlation coefficient between cotinine concentration and number of cigarettes smoked per day was 0.44.

    Serum cotinine concentration correlated more strongly than self-reported smoking with infant birth weight (r=0.246 vs. 0.200).

    In conclusion, this study showed that pregnant women accurately reported whether they smoked, but cotinine concentration was a better measure than self-report of the actual tobacco dose received.

    Mots-clés Pascal : Tabagisme, Gestation, Nicotine, Plasma sanguin, Taux, Marqueur biologique, Autoévaluation, Consommation, Tabac, Corrélation, Etude comparative, Homme, Epidémiologie, Etude cohorte, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Tobacco smoking, Pregnancy, Nicotine, Blood plasma, Rate, Biological marker, Self evaluation, Consumption, Tobacco, Correlation, Comparative study, Human, Epidemiology, Cohort study, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0426225

    Code Inist : 002B18C05C. Création : 25/01/1999.