logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Cannabis use, abuse, and dependence in a population-based sample of female twins.

    Article - En anglais

    Objective 

    The rate of cannabis use by women has been increasing in recent decades.

    This study examined the etiology of cannabis use and abuse among women and the possible role of genetic risk factors.

    Method 

    Unselected individual twins (N=1,934) from female-female pairs ascertained through a population-based registry, including both members of 485 monozygotic pairs and of 335 dizygotic pairs, were interviewed by telephone to assess lifetime cannabis use, heavy use, abuse, and dependence as defined by DSM-IV criteria.

    Biometric model fitting was performed with the Mx computer package.

    Results 

    The prevalences of lifetime cannabis use, heavy use, abuse, and dependence were 47.9%, 6.7%, 7.2%, and 2.2%, respectively.

    Model fitting suggested that twins'resemblance for liability to cannabis use was due to both genetic and familial-environmental factors, while twins'resemblance for heavy cannabis use and abuse and symptoms of dependence resulted solely from genetic factors, with heritabilities ranging from 62% to 79%. The frequency of adolescent social contact between co-twins, which was greater among monozygotic than among dizygotic twins, predicted the twins'resemblance in cannabis use.

    However, further analyses suggested that the heritability of cannabis use was at most modestly inflated by such social factors. (...)

    Mots-clés Pascal : Consommation, Dépendance, Cannabis, Cannabidaceae, Dicotyledones, Angiospermae, Spermatophyta, Etude familiale, Jumeau, Prévalence, Epidémiologie, Santé mentale, Déterminisme génétique, Milieu familial, Environnement social, Toxicomanie, Homme, Femelle, Facteur risque, Abus

    Mots-clés Pascal anglais : Consumption, Dependence, Cannabis, Cannabidaceae, Dicotyledones, Angiospermae, Spermatophyta, Family study, Twin, Prevalence, Epidemiology, Mental health, Genetic determinism, Family environment, Social environment, Drug addiction, Human, Female, Risk factor, Abuse

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0425726

    Code Inist : 002B18C05A. Création : 25/01/1999.