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  1. National use and effectiveness of bêta-blockers for the treatment of elderly patients after acute myocardial infarction national cooperative cardiovascular project.

    Article - En anglais

    Context. - Despite the importance of bêta-blockers for secondary prevention after acute myocardial infarction (AMI), several studies have suggested that they are substantially underutilized, particularly in older patients.


    - To describe the contemporary national pattern of bêta-blocker prescription at hospital discharge among patients aged 65 years or older with an AMI, to identify the most important predictors of the prescribed use of bêta-blockers at discharge, and to determine the independent association between bêta-blockers at discharge and mortality in clinical practice.


    - Retrospective cohort study using data created from medical charts and administrative files.


    - Acute care nongovernmental hospitals in the United States.


    - National cohort of 115015 eligible patients aged 65 years or older who survived hospitalization with a confirmed AMI in 1994 or 1995.

    Main Outcome Measures

    - bêta-Blocker as a discharge medication and mortality in the year after discharge.


    - Among the 45 308 patients without contraindications to bêta-blockers, 22 665 (50.0%) had a bêta-blocker as a discharge medication.

    There was significant variation by state, ranging from 30.3% to 77.1%. Of the 36 795 patients who were not receiving bêta-blocker therapy on admission, 16 006 (43.5%) had therapy initiated on or before discharge. (...)

    Mots-clés Pascal : Infarctus, Myocarde, Aigu, Bloquant bêta-adrénergique, Efficacité traitement, Chimiothérapie, Etude cohorte, Vieillard, Homme, Evaluation, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie

    Mots-clés Pascal anglais : Infarct, Myocardium, Acute, Beta blocking agent, Treatment efficiency, Chemotherapy, Cohort study, Elderly, Human, Evaluation, United States, North America, America, Cardiovascular disease, Coronary heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0418535

    Code Inist : 002B02F03. Création : 25/01/1999.