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  1. Zur gegenwärtigen Hepatitis-B-Epidemiologie in Deutschland.

    Article - En allemand

    Traduction en anglais : Studies on hepatitis B epidemiology in Germany.

    Studies on Hepatitis B Epidemiology in Germany : Hepatitis B (HB) is the most common occupational hazard for health care workers.

    On the other hand 90% of the notified HB cases in Germany are observed among the general population (including other high-risk groups like i.v. drug abusers etc.). About 350 million persons all over the world are carriers of the hepatitis B virus (HBV).

    The availaibility of effective HB vaccines since 1982 made a control of HB possible.

    In this communication we report on epidemiological changes due to hepatitis B vaccination in a large university hospital in Germany.

    Health care workers and non-health care workers occupied at Freiburg university hospital were tested for HBV markers in 1984/85 (n=4218), 1989/90 (n=4081) and 1994/95 (n=4022) during routine occupational health check-ups.

    Vaccinations were performed using a plasma-derived vaccine (1984/85) or a vaccine obtained by genetic engineering, respectively (1989/90,1994/95) In 1984/85 prevalence of anti-HBs/HBc in German health care workers (12.4%) was 2.5 times higher than the one in non-health care workers (4.9%), in 1994/95 anti-HBs/HBc prevalence in both groups (4.4 vs. 4.5%) was comparable.

    On the other hand HBV carriage in persons occupied in professions without blood contact increased from 1984/85 (0.5%) to 1994/95 (1.1%). Therefore, the number of HBV carriers (ca. 1.1 millions) in Germany can be roughly estimated. (...)

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Epidémiologie, Homme, Sérologie, Vaccination, Prévention, Allemagne, Europe, Exposition professionnelle, Non professionnel, Personnel, Milieu hospitalier, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Epidemiology, Human, Serology, Vaccination, Prevention, Germany, Europe, Occupational exposure, Non occupational, Personnel, Hospital environment, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0414982

    Code Inist : 002B05C02G. Création : 25/01/1999.