In order to assess the prevalence of leiomyomata in patients diagnosed with acromegaly, files of all women so diagnosed were obtained (n=25).
Eight of these patients had undergone hysterectomy.
In eight of the remaining patients, assessment of the uterus was performed by gynaecological examination and transvaginal ultrasound.
The prevalence of leiomyomata was 81% (13/16) in patients who had undergone hysterectomy (8/8) or who underwent gynaecological examination (5/8).
In conclusion, the very high prevalence of leiomyomata in patients diagnosed with acromegaly warrants the inclusion of growth hormone excess as a cause of leiomyomata.
Leiomyomata are a feature of the organomegalic syndrome associated with acromegaly.
Mots-clés Pascal : Acromégalie, Prévalence, Epidémiologie, Léiomyomatose, Utérus, STH, Endocrinopathie, Hypophyse pathologie, Système ostéoarticulaire pathologie, Utérus pathologie, Appareil génital femelle pathologie, Tumeur bénigne, Hormone adénohypophysaire, Homme, Femelle
Mots-clés Pascal anglais : Acromegaly, Prevalence, Epidemiology, Leiomyomata, Uterus, STH, Endocrinopathy, Pituitary diseases, Diseases of the osteoarticular system, Uterine diseases, Female genital diseases, Benign neoplasm, Adenohypophyseal hormone, Human, Female
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0414735
Code Inist : 002B20C02. Création : 25/01/1999.