This study examined the correlates of clinical gallbladder disease among US adults and whether serum ascorbic acid levels are associated with a decreased prevalence of gallbladder disease.
Cross-sectional analyses of data from the Second National Health and Nutrition Examination Survey were conducted.
A total of 384 women (8%) and 107 men (3%) reported a history of gallstone disease, and 347 women (7%) and 81 men (2%) reported a history of cholecystectomy.
An inverted U-shaped relation was found between serum ascorbic acid level and clinical gallbladder disease among women but not among women but not among men.
Ascorbic acid, which affects the catabolism of cholesterol to bile acids and, in turn, the development of gallbladder disease in experimental animals, may reduce the risk of clinical gallbladder disease in humans.
Mots-clés Pascal : Voie biliaire pathologie, Vésicule biliaire, Acide ascorbique, Taux, Plasma sanguin, Régime alimentaire, Epidémiologie, Prévalence, Facteur risque, Adulte, Homme, Etats Unis, Amérique du Nord, Amérique, Prévention, Appareil digestif pathologie
Mots-clés Pascal anglais : Biliary tract disease, Gallbladder, Ascorbic acid, Rate, Blood plasma, Diet, Epidemiology, Prevalence, Risk factor, Adult, Human, United States, North America, America, Prevention, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0413842
Code Inist : 002B13C03. Création : 25/01/1999.