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  1. Mortality in the first 2 years among infants born to human immunodeficiency virus-infected women in Harare, Zimbabwe.

    Article - En anglais

    Transmission of human immunodeficiency virus (HIV) and mortality was studied among infants of infected women in Zimbabwe.

    Of 367 infants born to HIV-infected women, 72 (19.6%) died compared with 20 (5.4%) of 372 infants of uninfected women (P<. 01).

    Infection by HIV DNA polymerase chain reaction among infants who survived>7 days and died within 2 years could be assessed in 87% (58/67) of infants of infected women and 83% (516) of infants of uninfected women ; transmission occurred in 40 of 58 infants.

    Among 27 infected infants tested at birth, 19 (70%), 5 (19%), and 3 (11%) were apparently infected via in utero, intrapartum or early postpartum, and late postpartum transmission, respectively.

    The majority of HIV-infected infants who died in the first 2 years of life were likely to have acquired in utero infection.

    Mots-clés Pascal : Virus HIV1, Virus immunodéficience humaine, Lentivirus, Retroviridae, Virus, Nourrisson, Homme, Transmission mère enfant, Epidémiologie, Etude longitudinale, Mortalité, Séropositivité, SIDA, Virose, Infection, Zimbabwe, Afrique, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : HIV-1 virus, Human immunodeficiency virus, Lentivirus, Retroviridae, Virus, Infant, Human, Mother to child transmission, Epidemiology, Follow up study, Mortality, Seropositivity, AIDS, Viral disease, Infection, Zimbabwe, Africa, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0406807

    Code Inist : 002B05C02D. Création : 25/01/1999.