Incidence and risk factors for stroke in an occupational cohort : The PROCAM study.
Background and Purpose-The purpose of this study was to assess the incidence of stroke and the magnitude of classic stroke risk factors in an occupational cohort of white-collar and blue-collar workers.
Methods-We studied a prospective cohort of 12 866 male employees, aged 30 to 65 years, in 52 companies in northwestern Germany, with an average follow-up of 7.2 years.
Participants were free of self-reported stroke, transient ischemic attack, and myocardial infarction at baseline.
Physical examination, blood tests, and a face-to-face interview to assess presence of various risk factors were performed at the workplace.
Follow-up was done by standardized mailed questionnaire.
Main outcome measure was first stroke occurrence.
Overall stroke incidence was 42.4 per 100 000 person-years, increasing from 10.1 per 100 000 person-years in the age category 30 to 39 years to 33.6,80.6, and 159.2 per 100 000 person-years in the age categories 40 to 49,50 to 59, and 60 years and older, respectively.
After adjustment for potential confounders, the relative risks of total stroke associated with systolic blood pressure ¾120,121 to 140, and =141 mm Hg were 1.00 (reference), 2.99 (95% confidence interval, 0.85 to 10.49), and 5.56 (1.56 to 19.88).
The risks associated with smoking status of never/past, ¾20 cigarettes per day, and>20 cigarettes per day) were 1.00 (reference), 1.65 (0.62 to 4.42), and 3.56 (1.78 to 7.15), respectively. (...)
Mots-clés Pascal : Accident cérébrovasculaire, Médecine travail, Allemagne, Europe, Epidémiologie, Incidence, Facteur risque, Homme, Travailleur, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Stroke, Occupational medicine, Germany, Europe, Epidemiology, Incidence, Risk factor, Human, Worker, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0406355
Code Inist : 002B17C. Création : 25/01/1999.