We conducted a cross-sectional survey to determine the prevalence of gallstone disease (gallstone or cholecystectomy) in a random sample of the adult population of Guadalajara, Spain.
The sample stratified by age and sex was drawn from the municipal census.
Stratum sample sizes were proportional to population sizes and to the expected prevalence rates calculated through a meta-analysis of the European literature.
The screening protocol included a gallbladder ultrasonography, a questionnaire on personal and family history, a physical examination, and a blood sample for biochemical determinations.
The response rate was 61.2%. The overall prevalence of gallstone disease was 9.7% (95% Cl, 7.3-12.0).
Prevalence was higher (but not statistically significant) in women (11.5% ; 95% CI, 8.2-14.7) than in men (7.8% ; 95% CI, 4.6-11.1).
After controlling for confounding by multiple logistic regression, increasing age, body mass index, dyspeptic symptoms, smoking habit, and use of hypolipidemic drugs were positively associated with gallstone disease.
Total serum cholesterol and alcohol consumption were negatively associated.
Mots-clés Pascal : Lithiase, Vésicule biliaire, Calcul biliaire, Epidémiologie, Prévalence, Adulte, Homme, Etude transversale, Sexe, Facteur risque, Espagne, Europe, Voie biliaire pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Lithiasis, Gallbladder, Biliary stone, Epidemiology, Prevalence, Adult, Human, Cross sectional study, Sex, Risk factor, Spain, Europe, Biliary tract disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0404693
Code Inist : 002B13C03. Création : 25/01/1999.