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  1. Anonymous unlinked testing as a sentinel approach : experience in Germany.

    Article, Communication - En anglais

    Hannover Sentinel Workshop. Hannover, DEU, 1996/03/01.

    Study objective-To establish a laboratory sentinel as a supplementary instrument for monitoring the seroprevalence of HIV among childbearing women as a proxy to the heterosexually active population.

    Design/Setting-Anonymous unlinked testing of neonatal dried blood spots has been performed in central laboratories of three federal states since 1993.

    The survey uses residual dried blood spots collected on Guthrie cards for screening of infants for metabolic disorders.

    These are eluted and tested for HIV antibodies.

    Data retained with the specimen are only district of residence along with year and month of birth.

    Participants-Because maternal IgG crosses the placenta before birth, the presence of antibodies in newborns reflects the infection status of the mother.

    Childbearing women are fairly representative for the heterosexually active general population.

    Main results-The observed HIV prevalence in childbearing women of less than 1 per thousand confirms the assumption ofa low rate of HIV infection in the general population.

    Significant time trends could not be detected, but HIV prevalence was higher in metropolitan compared with rural areas.

    Conclusions-Laboratory sentinels in general and the anonymous unlinked testing of neonatal dried blood spots in particular can supply additional information on HIV seroprevalence. (...)

    Mots-clés Pascal : SIDA, Virose, Infection, Prévalence, Sérologie, Surveillance sanitaire, Réseau, Laboratoire, Dépistage, Nouveau né, Homme, Allemagne, Europe, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Prevalence, Serology, Sanitary surveillance, Network, Laboratory, Medical screening, Newborn, Human, Germany, Europe, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0397223

    Code Inist : 002B30A01C. Création : 25/01/1999.