Control group characteristics and study outcomes : empirical data from a study on mortality of patients with type 2 diabetes mellitus in Dutch general practice.
Hannover Sentinel Workshop. Hannover, DEU, 1996/03/01.
Study objective-Control group characteristics as comorbidity and chronic psychosocial problems may play an important part in study outcomes.
A primary care data base was used to quantify the effects of varying the case mix of participants.
Design-Historical cohort study.
Setting-Data were collected from 1967-1996 in four Dutch general practices performing the Continuous Morbidity Registration Nijmegen.
Patients and controls-All newly diagnosed type 2 diabetic patients in the period 1967-1989 fulfilling the WHO criteria (n=265) ; for each type 2 diabetic patient a control was matched for practice, sex, age, and social class ; from these controls subgroups were selected based on the absence of different types of morbidity ; these subgroups were also matched for practice, sex, age, and social class.
Main results-The relative risk of mortality in type 2 diabetic patients in comparison with various subsets of controls ranged from 1.33 (95% CI 0.97,1.81) to 2.16 (95% CI 1.46,3.20).
Conclusion-Control group characteristics as comorbidity and chronic psychosocial problems turned out to influence the risk estimation in a cohort study.
General practice data enhance the study of these aspects.
Mots-clés Pascal : Diabète, Mortalité, Recrutement, Homme, Base donnée, Soin santé primaire, Antécédent, Facteur sociodémographique, Association morbide, Pays Bas, Europe, Endocrinopathie, Témoin
Mots-clés Pascal anglais : Diabetes mellitus, Mortality, Recruitment, Human, Database, Primary health care, Antecedent, Sociodemographic factor, Concomitant disease, Netherlands, Europe, Endocrinopathy
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0397206
Code Inist : 002B30A01C. Création : 25/01/1999.