Background A number of studies have reported that increased consumption of natural products reduced the risk of cancer.
Our previous case-control studies have shown a significant reduction in the risk of cancer development among those who regularly consumed ginseng.
We conducted a prospective cohort study to evaluate the preventive effect of ginseng against cancer on a population residing in a ginseng cultivation area on the basis of the result of case-control studies.
Methods This study was conducted in Kangwha-eup from August 1987 to December 1992.
We studied 4634 people over 40 years old who completed a questionnaire on ginseng intake.
In an attempt to obtain detailed information about ginseng intake, we asked them to specify their age at initial intake, their frequency and duration of ginseng intake, the kind of ginseng, etc.
Multiple logistic regression was used to estimate relative risks (RR) when controlling simultaneously for covariates.
Results Ginseng consumers had a decreased risk (RR=0.40,95% confidence interval [CI] : 0.28-0.56) compared with non-consumers.
On the type of ginseng, the RR was 0.31 (95% CI : 0.13-0.74) for fresh ginseng extract consumers and 0.34 (95% Cl : 0.20-0.53) for consumers of multiple combinations.
There was no cancer death among 24 red ginseng consumers.
There was a decreased risk with a rise in the frequency of ginseng intake, showing a dose-response relationship.
The RR of ginseng consumers were 0.33 (95% CI : 0.18-0. (...)
Mots-clés Pascal : Ginseng, Consommation alimentaire, Tumeur maligne, Mortalité, Morbidité, Etude cohorte, Prévention, Homme, Epidémiologie, Corée, Asie, Alimentation
Mots-clés Pascal anglais : Ginseng, Food intake, Malignant tumor, Mortality, Morbidity, Cohort study, Prevention, Human, Epidemiology, Korea, Asia, Feeding
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0394896
Code Inist : 002B04E05. Création : 25/01/1999.