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  1. Antacid (A02A) and antiulcer (A02B) drug prescription patterns : Predicting factors, dosage and treatment duration.

    Article - En anglais


    A study is made of the pharmaco-epidemiology of antacid (ATC class A02A) and antiulcer (A02B) drug prescriptions during the year 1992.

    Methods ; Prescription data were extracted from 1941 case histories of patients over 15 years old from four health care centers in the Valencian Community (Spain).

    Dosage and treatment duration were evaluated. along with the way in which morbidity, self-evaluated health. the demographic pattern and lifestyle characteristics influence drug prescription.


    The proportion of drug prescriptions increased with age in both sexes (p<0.01).

    Drug use depended mainly on chronic diseases.

    In prescribing antacids. the most influential diagnosis was gastritis (ICD 534, OR : 157), followed by duodenal ulcer (ICD 532, OR : 152) and gastric ulcer (ICD 531, OR : 122), other gastrointestinal disorders (ICD 66, OR : 54) and undefined diagnoses (OR : 15).

    In the prescription of antiulcer drugs, the most influential diagnoses were gastric and duodenal ulcer (OR : 380 and 342, respectively), and a significant relation was observed with the diagnosis of osteomuscular diseases (OR : 6).

    Lifestyle and demographic pattern were of marginal importance.

    The estimated duration of treatment was 85 days.

    No significant differences were observed in either treatment duration or administered doses of almagate. ranitidine and omeprazole with respect to sex, age or diagnosis.


    Prolonged treatment is common for acid suppression. (...)

    Mots-clés Pascal : Antiacide, Antiulcéreux, Médicament, Prescription médicale, Durée, Epidémiologie, Posologie, Chimiothérapie, Traitement, Homme, Espagne, Europe

    Mots-clés Pascal anglais : Antiacid, Antiulcer agent, Drug, Medical prescription, Duration, Epidemiology, Posology, Chemotherapy, Treatment, Human, Spain, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0394790

    Code Inist : 002B02H. Création : 25/01/1999.