Background Although colorectal cancer rates are low among most groups of Native Americans in North America, rates for Alaska Natives have been substantially elevated compared with US rates for all races combined.
Methods To better describe the epidemiology of colorectal cancer incidence and survival among Alaska Natives, stratified by gender and tribal/ethnic affiliation, we examined data collected by the Alaska Native Cancer Registry 1969-1993.
We calculated age-adjusted and age-specific incidence as well as actuarial survival rates, and examined histological type, site, stage at diagnosis, and treatment.
We compared these data to colorectal cancer data from whites living in western Washington.
Results In all, 587 colorectal cancer cases were identified among Alaska Natives over the 25-year period, for an age-adjusted annual incidence rate of 71.4/100 000 in women, and 69.3/100 000 in men.
Compared to Alaska Indians, colon cancer rates were significantly higher in Aleuts (relative risk [RR]=1.6,95% CI : 1.2-2.2) and in Eskimos (RR=1.5,95% CI : 1.2-1.8), while rectal cancer rates did not differ by race/ethnicity.
Alaska Natives experienced a 50% higher incidence rate of colorectal cancer overall compared to western Washington whites (RR=1.5,95% CI : 1.3-1.6), although rectal cancer rates were similar in the two populations. (...)
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Facteur risque, Epidémiologie, Incidence, Survie, Mortalité, Homme, Etats Unis, Amérique du Nord, Amérique, Ethnie, Alaska, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Risk factor, Epidemiology, Incidence, Survival, Mortality, Human, United States, North America, America, Ethnic group, Alaska, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0394654
Code Inist : 002B13C01. Création : 25/01/1999.