Patients with alcoholic liver disease have an increased prevalence of viral hepatitis.
However, the role of demographic characteristics has not been adequately delineated.
Therefore, we examined and compared the seroprevalences of hepatitis B and C in Israeli alcoholic patients to that of blood donors control group by their country of birth and origin.
Hepatitis B surface antigen. hepatitis B core antibody and hepatitis C virus antibody testing (second generation ELISA) and a confirmatory recombinant immunoblot assay was performed on 496 alcoholic attending an alcoholic abstinence program and compared to 193,806 randomly non-alcoholic blood donors on the basis of their country of birth.
Three hundred twenty-eight alcoholic patients (66%) were immigrants and Israeli born Jews and 168 (34%) were Israeli Arabs.
Of the 496 alcoholic patients, 24 (4.8%) were HBsAg positive, 38 (7.6%) were anti HCV positive, and 2 (North African Jews) were positive for both markers.
HBsAg was detected in 13 (3.9%) immigrant and Israeli Jews and 11 (6.5%) Israeli Arabs, significantly higher than in the adjusted non alcoholic blood donors (p<0.01).
Anti-HCV was detected in 33 (10%) immigrants and Israeli Jews and 5 (2.9%) Israeli Arabs, significantly higher than in the control group (p<0.005). (...)
Mots-clés Pascal : Alcoolisme, Hépatite virale B, Virose, Infection, Hépatite virale C, Marqueur biologique, Epidémiologie, Incidence, Sérologie, Homme, Israël, Asie, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Alcoholism, Viral hepatitis B, Viral disease, Infection, Viral hepatitis C, Biological marker, Epidemiology, Incidence, Serology, Human, Israel, Asia, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0394454
Code Inist : 002B05C02G. Création : 25/01/1999.