Objectives-To estimate the incidence rate of Guillain-Barré syndrome variants in an unselected population and to describe their clinical features and prognosis.
Methods-A two year prospective multicentre study on the incidence and prognosis of Guillain-Barré syndrome was performed in Emilia-Romagna, northern Italy (3 909 512 inhabitants).
A surveillance system was instituted within the study area, which comprised all the neurological departments, private and public general hospitals, and practising neurologists.
The international classification of diseases (ICD) codes 357.
XX (any peripheral neuropathy) of hospital discharges were also reviewed.
Data were separately analysed for Miller Fisher syndrome and other Guillain-Barré syndrome variants.
During the study period 18 patients with Guillain-Barré syndrome variants including seven with Miller Fisher syndrome were recruited ; the incidence rates were 0.14/100 000/year (95% confidence interval (95% CI) 0.07-0.25) for Guillain-Barré syndrome variants (excluding Miller Fisher syndrome) and 0.091100 0001year (95% CI 0.04-0.18) for Miller Fisher syndrome.
Guillain-Barré syndrome variants alone (excluding Miller Fisher syndrome) accounted for 10.5% of total cases.
Death and relapses were not found.
Details of clinical, electrophysiological, and CSF findings of Guillain-Barré syndrome variants are provided. (...)
Mots-clés Pascal : Polyradiculonévrite Guillain Barré, Variant, Forme clinique, Polyradiculonévrite Fisher, Italie, Europe, Symptomatologie, Electrodiagnostic, Diagnostic, Incidence, Epidémiologie, Pronostic, Homme, Système nerveux pathologie, Nerf périphérique pathologie, Maladie inflammatoire, Oculomotricité syndrome, Ophtalmoplégie, Oeil pathologie
Mots-clés Pascal anglais : Guillain Barré syndrome, Variant, Clinical form, Fisher syndrome, Italy, Europe, Symptomatology, Electrodiagnosis, Diagnosis, Incidence, Epidemiology, Prognosis, Human, Nervous system diseases, Peripheral nerve disease, Inflammatory disease, Oculomotor syndrome, Ophthalmoplegia, Eye disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0388511
Code Inist : 002B17F. Création : 25/01/1999.