A total of 911 Danish'children under 15 years of age were treated for an intracranial tumour in the 25-five year period 1960-1984.
All cases were followed up to the end of 1994 or to emigration or death if one of these came sooner.
The mean annual incidence was 32.5 per million children with a slight increase over the 25 years.
The male/female ratio was 1.15 and close to the M/F ratio for the entire Danish population of children.
Of the tumours, 46% were located in the supratentorial and 54% in the infratentorial compartment, and 94% were verified histologically.
In order of frequency the most common types were astrocytomas (all grades, 35%), medulloblastomas (20%), ependymomas (14%), and craniopharyngiomas (5%). Total removal of the tumour was performed in 277 and partial removal, including biopsy, in 490 children.
In 57 patients a shunt operation only was performed, and 87 children did not have an operation or died before the correct diagnosis was established.
Radiotherapy was administered in 55%. The outcome depended on extent of removal, radiation, location and histology of the tumour.
Most (784 or 86%) of the children survived more than 1 month after diagnosis or operation, and 353 children (39% of the whole series, 47% of those alive more than 1 month after diagnosis) were alive at follow-up. (...)
Mots-clés Pascal : Tumeur, Intracrânien, Localisation, Type histologique, Survie, Long terme, Danemark, Europe, Incidence, Epidémiologie, Pronostic, Enfant, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie
Mots-clés Pascal anglais : Tumor, Intracranial, Localization, Histological type, Survival, Long term, Denmark, Europe, Incidence, Epidemiology, Prognosis, Child, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0386784
Code Inist : 002B17E. Création : 25/01/1999.