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  1. Serum cholesterol and coronary artery disease in populations with low cholesterol levels : The Indian paradox.

    Article - En anglais

    Objective, To examine the relation between serum cholesterol and coronary artery disease prevalence below the range of cholesterol values generally observed in developed countries.

    Design and Setting 

    Cross-sectional survey of two randomly selected villages from Moradabad district and 20 randomly selected streets in the city of Moradabad.

    Subjects and methods, 3575 Indians, aged 25-64 years including 1769 rural (894 men, 875 women) and 1806 urban (904 men, 902 women) subjects.

    The survey methods were questionnaires, physical examination and electrocardiography.


    The overall prevalences of coronary artery disease were 9.0% in urban and 3.3% in rural subjects and the prevalences were significantly (P<0.001) higher in men compared to women in both urban (11.0 vs. 6.9%) and rural subjects (3.9 vs. 2.6%). The average serum cholesterol concentrations were 4.91 mmol/l in urban and 4.22 mmol/l in rural subjects without any sex differences.

    The prevalences of coronary artery disease were significantly higher among subjects with low and high serum cholesterol concentration compared to subjects with very low cholesterol and showed a positive relation with serum cholesterol within the range of serum cholesterol level studied in both rural and urban in both sexes.

    Among subjects with low serum cholesterol, there was a higher prevalence of coronary risk factors, hypertension, diabetes, obesity and sedentary lifestyle. (...)

    Mots-clés Pascal : Cardiopathie coronaire, Homme, Inde, Asie, Cholestérol, Facteur risque, Epidémiologie, Exploration, Prévalence, Appareil circulatoire pathologie, Lipide

    Mots-clés Pascal anglais : Coronary heart disease, Human, India, Asia, Cholesterol, Risk factor, Epidemiology, Exploration, Prevalence, Cardiovascular disease, Lipids

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0377218

    Code Inist : 002B12A03. Création : 25/01/1999.