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  1. Gender differences in baseline variables, therapies and outcomes in Chinese patients with acute myocardial infarction.

    Article - En anglais

    We prospectively studied the gender differences of baseline variables, therapies, and outcomes among a cohort of 369 Chinese patients with acute myocardial infarction from 1990 to 1995.

    There were 277 male and 92 female patients.

    The male gender had a younger mean (±SD) age (61.5±10.7 vs. 67.1±11.7 years, P<0.0001).

    Hypercholesterolemia (201.2±44.2 vs. 187.5±43.7 mg/dl.

    P=0.0111) and obesity (25.0 vs. 15.9%, P=0.0494) were more prominent in the female.

    Smoking was more prevalent in the male (78.3 vs. 18.5%, P<0.0001).

    The male group also had more frequent use of thrombolytic agents (19.1 vs. 9.8%, P=0.0377), bêta-blockers (61.7 vs. 47.8%, P=0.0191) and heparin (25.3 vs. 12.0%, P=0.0075) ; but less use of angiotensin-converting enzyme inhibitors (6.9 vs. 15.2%, P=0.0149).

    The condition on admission was worse in the female group (Killip classification (1.5±0.9 vs. 1.9±1.0, P=0.0022), myocardial failure (8.7 vs. 2.9%, P=0.0178) and cardiomegaly (65.2 vs. 53.1%, P=0.0419).

    During a follow-up duration of 26.4±24.1 and 22.9±23.9 months respectively, the mortality rate was lower in the male (19.5 VS, 30.4%, P=0.0288).

    However after adjustment for the effect of age, thc differences in Killip classification, myocardial failure, cardiomegaly and mortality became insignificant.

    Mots-clés Pascal : Infarctus, Myocarde, Chine, Asie, Homme, Femelle, Mâle, Sexe, Traitement, Evolution, Facteur risque, Chimiothérapie, Pronostic, Etude comparative, Epidémiologie, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie

    Mots-clés Pascal anglais : Infarct, Myocardium, China, Asia, Human, Female, Male, Sex, Treatment, Evolution, Risk factor, Chemotherapy, Prognosis, Comparative study, Epidemiology, Cardiovascular disease, Coronary heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0374757

    Code Inist : 002B12A03. Création : 25/01/1999.