A prospective study of acute poisonings in Finnish hospital patients.
We have carried out a prospective study of all adult patients presenting with acute poisoning during one month to the Helsinki University Central Hospital (Meilahti Hospital).
Two hundred and twenty-six cases of acute poisoning (113 males and 113 females) presented to the emergency department.
Most cases in both men (66%) and women (67%) involved alcohol.
As to drugs, psychotropic agents predominated in both men and women.
The frequency of patient presentation peaked between 7 p.m. and 9 p.m. and was lowest between 8 a.m. and 10 a.m. In most cases, the delay from ingestion of the poison to presentation was longer than 4 h. The clinical status of the patients on arrival was generally good ; more than half (55%) of them were fully awake.
Serious symptoms (e.g. unconsciousness, insufficient respiration necessitating intubation, aspiration, convulsions or hypotension) occurred in 15% of the presentations.
There were no fatalities. 4 One hundred and thirty-five patients (60%) received at least one 50-g dose of activated charcoal.
However, charcoal was given in 86% of the cases of drug poisoning.
Gastric lavage was performed in 112 cases (50%), and 106 cases (47%) involved both gastric lavage and administration of charcoal.
Twenty-one patients received antidotes (flumazenil, calcium gluconate or naloxone) and three patients were hemodialysed. 5 Of the 226 cases, 142 (63%) were managed solely in the emergency department. (...)
Mots-clés Pascal : Intoxication, Hôpital, Epidémiologie, Finlande, Europe, Adulte, Homme, Réanimation, Traitement, Service urgence
Mots-clés Pascal anglais : Poisoning, Hospital, Epidemiology, Finland, Europe, Adult, Human, Resuscitation, Treatment, Emergency department
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0373105
Code Inist : 002B03B. Création : 25/01/1999.