The purpose of the present study was to determine if individuals with high levels of cardiorespiratory fitness have better levels of the cardiovascular disease (CVD) risk factors of total cholesterol (TC), HDL cholesterol (HDL), total cholesterol/HDL cholesterol ratio (TC/HDL), triglycerides (TG), and fibrinogen (FIB) when compared with those with low fitness, in 283 nonsmoking, postmenopausal women.
Second, we examined the relation between fitness and CVD risk after controlling for use of hormones and other possible confounding factors.
These analyses were done on a subset of nonsmoking, postmenopausal women in the Aerobics Center Longitudinal Study (ACLS).
Records of postmenopausal women who completed a preventive medicine physical examination between 1987 and 1995 were examined.
Cardiorespiratory fitness level was determined by total treadmill time to exhaustion on a graded exercise test ; CVD risk factors were assessed via blood analysis.
On cross-sectional regression analysis, fitness was significantly associated (P<0.005) with TC (r2=0.08), TC/HDL (r2=0.12), TG (r2=0.09), and FIB (r2=0.06), and an increase in HDL (r2=0.04).
After controlling for hormone status, age, year of testing, and blood glucose, each outcome variable remained significantly associated with cardiorespiratory fitness (P<0.05). (...)
Mots-clés Pascal : Facteur risque, Cardiopathie coronaire, Postménopause, Aptitude physique, Non fumeur, Epidémiologie, Traitement substitutif, Oestrogène, Progestérone, Appareil circulatoire pathologie, Homme, Femelle
Mots-clés Pascal anglais : Risk factor, Coronary heart disease, Postmenopause, Physical fitness, Non smoker, Epidemiology, Replacement therapy, Estrogen, Progesterone, Cardiovascular disease, Human, Female
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0367104
Code Inist : 002B02O. Création : 25/01/1999.