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  1. Influences of cardiorespiratory fitness levels and other predictors on cardiovascular disease mortality in men.

    Article - En anglais


    This investigation quantifies the relation between cardiorespiratory fitness levels and cardiovascular disease (CVD) mortality within strata of other CVD predictors.


    Participants included 25,341 male Cooper Clinic patients who underwent a maximal graded exercise test.

    CVD death rates were determined for low (least fit one-fifth), moderate (next two-fifths), and high (top two-fifths) cardiorespiratory fitness categories by strata of smoking habit, blood cholesterol level, resting blood pressure, and health status.

    There were 226 cardiovascular deaths during 211,996 man-years of follow-up.


    For individuals with none of the major CVD predictors (smoking, elevated resting systolic blood pressure, elevated blood cholesterol), there was a strong inverse relation (P=0.001) between fitness level and CVD mortality.

    An inverse relation between CVD mortality and fitness level was seen within strata of cholesterol levels and health status.

    No evidence of a trend (P=0.60) for decreased mortality was seen across fitness levels for individuals with elevated systolic blood pressure ; however, a strong inverse gradient (P<0.001) was seen across fitness levels for individuals with normal systolic blood pressure.

    There was a tendency for association between high levels of fitness and decreased CVD mortality in smokers compared with low and moderately fit smokers (P<0.076). (...)

    Mots-clés Pascal : Aptitude physique, Cardiopathie coronaire, Mortalité, Epidémiologie, Facteur risque, Appareil circulatoire pathologie, Homme

    Mots-clés Pascal anglais : Physical fitness, Coronary heart disease, Mortality, Epidemiology, Risk factor, Cardiovascular disease, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0366789

    Code Inist : 002B12A03. Création : 25/01/1999.