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  1. Influences of cardiorespiratory fitness levels and other predictors on cardiovascular disease mortality in men.

    Article - En anglais

    Purpose 

    This investigation quantifies the relation between cardiorespiratory fitness levels and cardiovascular disease (CVD) mortality within strata of other CVD predictors.

    Methods 

    Participants included 25,341 male Cooper Clinic patients who underwent a maximal graded exercise test.

    CVD death rates were determined for low (least fit one-fifth), moderate (next two-fifths), and high (top two-fifths) cardiorespiratory fitness categories by strata of smoking habit, blood cholesterol level, resting blood pressure, and health status.

    There were 226 cardiovascular deaths during 211,996 man-years of follow-up.

    Results 

    For individuals with none of the major CVD predictors (smoking, elevated resting systolic blood pressure, elevated blood cholesterol), there was a strong inverse relation (P=0.001) between fitness level and CVD mortality.

    An inverse relation between CVD mortality and fitness level was seen within strata of cholesterol levels and health status.

    No evidence of a trend (P=0.60) for decreased mortality was seen across fitness levels for individuals with elevated systolic blood pressure ; however, a strong inverse gradient (P<0.001) was seen across fitness levels for individuals with normal systolic blood pressure.

    There was a tendency for association between high levels of fitness and decreased CVD mortality in smokers compared with low and moderately fit smokers (P<0.076). (...)

    Mots-clés Pascal : Aptitude physique, Cardiopathie coronaire, Mortalité, Epidémiologie, Facteur risque, Appareil circulatoire pathologie, Homme

    Mots-clés Pascal anglais : Physical fitness, Coronary heart disease, Mortality, Epidemiology, Risk factor, Cardiovascular disease, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0366789

    Code Inist : 002B12A03. Création : 25/01/1999.