The aim of this study was to obtain more accurate figures of the prevalence of cutaneous sensitivity to Hymenoptera venoms (HV) and its correlation with other parameters of atopy in a population of primary schoolchildren.
Parents filled out a structured questionnaire and children were tested with a panel of inhalant and food allergens as well as standardized freeze-dried extracts of HV.
Among the 1175 children who completed the study there was a personal history of rhinoconjunctivitis in 242 (20.8%) and a current wheezing in 114 (9.78%). Two-hundred twenty-eight (19.40%) children had a history of Hymenoptera sting (HS) reactions (224 or 19.06% of local reactions and 4 or 0.34% of local and systemic reactions).
Positive skin-prick tests (SPT) to any given HV extract were present in 43 children (3.66%). Most subjects had positive SPT to honey bee venom (35/1175 ; 2.98%) ; 17/1175 (1.45%) had positive SPT to wasp and only 12 subjects (1.02%) had positive SPT to polistes venom.
There was a correlation between a positive SPT to HV and the history of clinical reactions to HS (P=0.0026).
Positive SPT to at least one of the inhalant and food allergens tested were found in 353 subjects (30.04%). Factors such as age, sex, reactions to HV, positive SPT to mite. cat dander, grass, Alternaria, Parietaria, cow's milk, egg white and wheat were significantly associated with a positive SPT to HV using a univariate regression analysis. (...)
Mots-clés Pascal : Allergie, Venin, Hymenoptera, Insecta, Arthropoda, Invertebrata, Piqûre, Atopie, Prévalence, Epidémiologie, Italie, Europe, Enfant, Homme, Immunopathologie
Mots-clés Pascal anglais : Allergy, Venom, Hymenoptera, Insecta, Arthropoda, Invertebrata, Sting, Atopy, Prevalence, Epidemiology, Italy, Europe, Child, Human, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0356935
Code Inist : 002B06C04. Création : 25/01/1999.