International Symposium on Speciation of Elements in Toxicology and in Environmental and Biological Sciences. Port Douglas, AUS, 1997/09/15.
There are concerns that wearing chromium tanned leather gloves can provoke a relapse of hand dermatitis in chromium sensitive patients.
Various forms of chromium have different biological effects and the determination of total chromium (both soluble and insoluble), which often is used in clinical studies, may therefore not be an adequate measure of the adverse exposure.
However, investigations, where dissolution of hexavalent chromium from leather gloves has been experimentally studied, could not been found in the literature.
The aim of this pilot study was therefore to determine the total amount of chromium and the amount of sweat leachable chromium in different leather glove materials and also to apply samples of these materials in a patch test to chromium sensitive patients to see if they could provoke a reaction.
The results showed that chromium tanned leather contained about 3% (m/m) chromium.
Chromium can also be found in dyed vegetable tanned leather, probably emanating from the leather dye.
Small amounts (average 0.08% m/m) of leachable hexavalent chromium were found in both chromium and vegetable tanned leathers.
Thus, the risk of relapse of chromium dermatitis cannot be disregarded and further studies on the causes of relapse of chromium dermatitis are necessary.
Mots-clés Pascal : Chrome, Métal lourd, Exposition professionnelle, Vêtement protection, Gant, Cuir, Homme, Médecine travail, Spéciation, Allergie, Dermatite contact, Chrome VI, Immunopathologie, Peau pathologie
Mots-clés Pascal anglais : Chromium, Heavy metal, Occupational exposure, Safety clothing, Glove, Leather, Human, Occupational medicine, Speciation, Allergy, Contact dermatitis, Chromium VI, Immunopathology, Skin disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0348421
Code Inist : 002B03L05. Création : 27/11/1998.