Acute lower respiratory infection (ALRI) is one of the main causes of morbidity and mortality in small children.
The aim of this study was to determine the frequency, seasonality and association with clinical entities of respiratory syncytial virus (RSV) and adenoviruses in children with ALRI.
During 2 consecutive years (1991-1992), 168 children under 2 years of age hospitalized due to ALRI in a public pediatric hospital of Buenos Aires, Argentina, were studied.
RSV and adenoviruses were investigated on nasopharyngeal aspirates (NPA) by indirect immunofluorescence (IIF).
HEp-2 cells were used for adenovirus isolation.
RSV was detected in 36.3% and adenoviruses in 14.3°% of the cases (P<0.0001).
All adenoviruses detected by IIF were also isolated in culture.
Out of 61 RSV cases, 57% corresponded to bronchiolitis and 43% to pneumonia.
Ninety-two per cent of children with RSV were less than 1 year old and 70% were less than 5 months.
The highest number of RSV cases were observed during winter, with a clear peak in July.
Seventy-one per cent of adenovirus cases were associated with pneumonia and only 24% with bronchiolitis (P<0.02), and predominated in children older than 5 months of age (P<0.0001).
Adenoviruses were detected in almost all months of the year with a small peak at the end of winter and beginning of spring. (...)
Mots-clés Pascal : Virus respiratoire syncytial humain, Pneumovirus, Pneumovirinae, Paramyxoviridae, Mononegavirales, Virus, Adénovirus humain, Mastadenovirus, Adenoviridae, Virose, Infection, Appareil respiratoire, Nourrisson, Homme, Hospitalisation, Argentine, Amérique du Sud, Amérique, Epidémiologie
Mots-clés Pascal anglais : Human respiratory syncytial virus, Pneumovirus, Pneumovirinae, Paramyxoviridae, Mononegavirales, Virus, Human adenovirus, Mastadenovirus, Adenoviridae, Viral disease, Infection, Respiratory system, Infant, Human, Hospitalization, Argentina, South America, America, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0344511
Code Inist : 002A05C06. Création : 27/11/1998.