The ongoing vaccination campaign against hepatitis B (HB) for newborns of hepatitis B surface antigen (HBsAg) positive mothers and for 12-year-old subjects was evaluated in Naples, Italy, an area of relavely high HB endemicity.
Subjects were recruited by a random sampling procedure.
Among 2060 pregnant women studied, 1887 (91.6%) were screened for HBsAg.
HBsAg prevalence was 2.5% (47/1887).
Immunoprophylaxis according to the protocol (immunoglobulins within 24 h plus vaccine within 7 days after birth) was administered in 26 (55.3%) out of the 47 newborns of HBsAg positive mothers ; vaccination was delayed (later than 7 days after birth) for 14 (29.8%) infants ; in the remaining seven newborns (14.9%) were not given immunoglobulins at birth.
All infants were vaccinated.
Out of the 1000 adolescents sampled 130 (13%) were not found due to an inaccurate census list ; 727 (83.3%) of the 870 investigated had received a three-dose HB vaccine series.
Overall, the HB vaccination program in Italy is working well.
However, further efforts should be made to improve the efficacy and effectiveness of the campaign.
Mots-clés Pascal : Nouveau né, Homme, Enfant, Adolescent, Femelle, Gestation, Prévalence, Vaccination, Prévention, Immunoprophylaxie, Programme sanitaire, Hépatite virale B, Virose, Infection, Appareil digestif pathologie, Foie pathologie, Italie, Europe, Europe Sud
Mots-clés Pascal anglais : Newborn, Human, Child, Adolescent, Female, Pregnancy, Prevalence, Vaccination, Prevention, Immunoprophylaxis, Sanitary program, Viral hepatitis B, Viral disease, Infection, Digestive diseases, Hepatic disease, Italy, Europe, Southern Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0343723
Code Inist : 002B05A02. Création : 27/11/1998.