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  1. Secular trend in blood lead levels in a cohort of Mexico City children.

    Article - En anglais

    We determined the secular trend in blood lead levels in a cohort of 104 children born in Mexico City between 1987 and 1993.

    We grouped children by the calendar year in which they reached 6 mo of age and measured blood lead levels every 6 mo until they attained 36 mo of age.

    The overall geometric mean blood lead level was 9.6 mug/dl (range=1.5-59.5 mug/dl).

    A repeated measures analysis of variance revealed a highly significant linear trend in blood lead level with year (p<. 001) ; there was a maximum decrease of 7.6 mug/dl between 1989 and 1993.

    There was a highly significant quadratic age effect (p<. 001) ; blood lead levels rose between 6 and 18 mo of age and decreased thereafter.

    There was a marginally significant interaction between age of the child and year.

    Family use of lead-glazed pottery significantly elevated blood lead levels (p=028).

    The downward trend in blood lead levels during the time period of study corresponded to the reduction in various sources of lead exposure.

    Mots-clés Pascal : Plomb, Métal lourd, Polluant, Environnement, Relation temps réponse, Epidémiologie, Taux, Sang, Enfant, Homme, Milieu urbain, Mexique, Amérique Centrale, Amérique, Etude longitudinale, Tendance

    Mots-clés Pascal anglais : Lead, Heavy metal, Pollutant, Environment, Time response relation, Epidemiology, Rate, Blood, Child, Human, Urban environment, Mexico, Central America, America, Follow up study, Trend

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0343284

    Code Inist : 002B03M01. Création : 27/11/1998.