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  1. Are there risk factors for hepatitis B infection in inner-city adolescents that justify prevaccination screening ?

    Article - En anglais

    Purpose 

    This study was undertaken to determine if homelessness could serve as a marker for previous hepatitis B infection (HBI), and thus justify prevaccination screening.

    Methods 

    One hundred sexually active 13-21-year-olds (mean=17 years), 74% female, attending an inner-city hospital-based adolescent clinic (HOSP), and 48 sexually active 13-21-year-olds (mean=19 years), 40% female, attending a clinic based at an urban drop-in center (UDC) for street youth were consecutively enrolled, screened for HBI serum markers and administered a structured interview about sexual practices, sexual abuse, prior sexually transmitted diseases (STDs), and injection drug use.

    Results 

    For the HOSP group, 7% were homeless and 4% were HBI positive.

    In the UDC group, 96% were homeless and 23% were HBI positive.

    Homelessness was significantly associated with HBI (rhô<0.001), and this was corroborated by logistic regression analysis (rhô<0.01).

    Other factors significantly associated with HBI in adolescents included a history of anal sex (rhô <=0.002), anal-receptive sex (rhô <=0.01), genital Chlamydia (rhô <=0.03), prostitution (rhô <=0.03), and sexual abuse (rhô <=0.002).

    For both populations, gender, sexual orientation, intravenous drug use, and genital sex were not related to HBI.

    Conclusion 

    These data indicate that homelessness and associated high-risk sexual practices may be indications for prevaccination screening for HBI in adolescents.

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Facteur risque, Adolescent, Homme, Mode de vie, Sans domicile fixe, Sexualité, Relation sexuelle, Epidémiologie, New York, Etats Unis, Amérique du Nord, Amérique, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Risk factor, Adolescent, Human, Life habit, Homeless, Sexuality, Sexual intercourse, Epidemiology, New York, United States, North America, America, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0342684

    Code Inist : 002B05C02G. Création : 27/11/1998.