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  1. Drug use evaluation of ciprofloxacin : impact of educational efforts on appropriateness of use.

    Article - En anglais


    To evaluate the appropriateness of ciprofloxacin use in a 550-bed general hospital before and after an educational intervention.


    A drug use evaluation was carried out for 6 weeks, to examine the appropriateness of initiating therapy with ciprofloxacin, as judged by compliance with the hospital's protocols for antibiotic use.

    The results were distributed to all the hospital physicians, together with a review of the usage guidelines.

    Four months later the survey was repeated to examine the effects of this educational effort on the patterns of use.


    During the initial survey, 115 patients were treated with ciprofloxacin.

    During the follow-up 126 patients were treated with ciprofloxacin.

    The percentage of unjustified use had decreased from 31% to 13% at follow-up (P<0.005).

    Improvement was seen in all the hospital departments needing improvement and most significantly in the medical departments.

    The most frequent indication for use of the drug was urinary tract infection (86 patients (36%) in total in the two stages).

    The most significant improvement was in justified usage for urinary tract infections : from 65% in the initial stage to 88% in the second stage (P<0.025). (...)

    Mots-clés Pascal : Ciprofloxacine, Antibactérien, Antibiotique, Evaluation, Prescription médicale, Hôpital, Adaptation, Utilisation, Education santé, Fluoroquinolone dérivé, Quinolone dérivé

    Mots-clés Pascal anglais : Ciprofloxacin, Antibacterial agent, Antibiotic, Evaluation, Medical prescription, Hospital, Adaptation, Use, Health education, Fluoroquinolone derivatives, Quinolone derivatives

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0341542

    Code Inist : 002B02S02. Création : 27/11/1998.