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  1. Anwendung molekularbiologischer Methoden bei Berufskrankheiten-Feststellungsverfahren : Ein Diskussionsbeitrag.

    Article - En allemand

    Traduction en anglais : Methods of molecular biology used to settle questions of compensability of occupational diseases : a contribution to discussion.

    Recent findings in the field of molecular biology show that some organic carcinoma, in their genoms, wear a sort of « finger print » of the agent that caused their development.

    Already today it is possible to obtain precious additional information on the connection that may exist between hazardous workplace exposure and cancerous diseases by recoursing to special analytical methods which help localise mutations and identify their frequency spectrum.

    This is for instance the case for tumours of the liver, the skin and the kidneys.

    In accordance with the applying German legislation, molecular analyses come second in the hierarchy of decision criteria - right after exposure data - on condition that they contribute to concluding whether or not the intensity of dangerous exposure is the central cause for the development of a disease.

    Considering that in 1997 a first decision on the compensability of a work-induced cancer was taken on the basis of the mutation analysis, this approach is likely to gain in importance in the near future.

    Mots-clés Pascal : Méthode analyse, Biologie moléculaire, Tumeur maligne, Exposition professionnelle, Médecine travail, Homme, Séquence nucléotide, Mutation

    Mots-clés Pascal anglais : Analysis method, Molecular biology, Malignant tumor, Occupational exposure, Occupational medicine, Human, Nucleotide sequence, Mutation

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0341091

    Code Inist : 002B04A. Création : 27/11/1998.