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  1. Studying dynamics of the HIV epidemic : population-based data compared with sentinel surveillance in Zambia.

    Article - En anglais

    Objectives 

    To establish population-based HIV survey data in selected populations, and to assess the validity of extrapolation from HIV sentinel surveillance amongst antenatal clinic attenders (ANC) to the general population.

    Methods 

    In a population survey, adults aged = 15 years were selected by stratified random cluster sampling (n=4195).

    The survey was carried out in catchment populations of clinics used for national HIV surveillance.

    The methodology allows detailed comparisons of HIV infection patterns to be made in two areas (urban and rural).

    Whereas the sentinel surveillance used serum-based HIV testing, the population survey used saliva (93.5% consented to provide a saliva sample).

    Results 

    Surveillance of ANC tended to underestimate the overall HIV prevalence of the general population, but differences were not statistically significant.

    In the urban area, the adjusted overall HIV prevalence rate of ANC (aged 15-39 years) was 24.4% 195% confidence interval (Cl), 20.9-28.0] compared with 26.0% (95% Cl, 23.4-28.6) in the general population.

    The respective rural estimates were 12.5% (95% Cl, 9.3-15.6) versus 16.4% (95% Cl, 12.1-20.6).

    Age-specific prevalence rates showed ANC to overestimate infection in teenagers (aged 15-19 years), whereas in the reverse direction of those aged>30 years. (...)

    Mots-clés Pascal : SIDA, Virose, Infection, Epidémie, Prévalence, Epidémiologie, Estimation, Méthode, Surveillance sanitaire, Zambie, Afrique, Homme, Zone urbaine, Zone rurale, Evolution, Immunopathologie, Immunodéficit, Organisation santé

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Epidemic, Prevalence, Epidemiology, Estimation, Method, Sanitary surveillance, Zambia, Africa, Human, Urban area, Rural area, Evolution, Immunopathology, Immune deficiency, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0330818

    Code Inist : 002B05C02D. Création : 27/11/1998.