Methylmercury and inorganic mercury in serum-correlation to fish consumption and dental amalgam in a cohort of women born in 1922.
Methylmercury in serum (S-MeHg) was assessed from serum concentrations of total (S-TotHg) and inorganic mercury (S-InoHg), determined by cold vapor-atomic absorption spectrometry.
The samples were collected from 135 women on two occasions, in 1968-1969 and 1980-1981.
In a subgroup of 29 women, an association was found between S-MeHg and the amount of fish consumed in 1968-1969 (r=0.38, P=0.04).
The association was stronger (r=0.50 ; P=0.006) when the individuals'mean S-MeHg from 1968-1969 and 1980-1981 were plotted vs fish consumption 1968-1969.
In the group, as a whole, there was an association between S-InoHg and number of dental amalgam surfaces, in both 1968-1969 (r=0.48, P=0.0001) and 1980-1981 (r=0.57, P<0.0001).
The S-InoHg increased by approximately 0.1 nmol/L per amalgam tooth surface, corresponding to an uptake of approximately 0.2 mug/day per amalgam surface, but with considerable interindividual differences.
The levels were lower in 1980-1981 than in 1968-1969 for both MeHg and InoHg.
The medians and ranges (nmol/L) were for MeHg 1968-1969 :
3.6 (0.3-11.9) ;
MeHg 1980-1981,2.0 (-0.4-8.7) ;
InoHg 1968-1969,3.3 (0.7-11.8) ;
InoHg 1980-1981,1.7 (0.1-11.8) ;
TotHg 1968-1969,7.2 (1.9-18.8) ;
and TotHg 1980-1981,3.9 (1.0-14.2).
The decrease in S-MeHg is probably due to a decreased consumption of MeHg via contaminated fish. (...)
Mots-clés Pascal : Mercure, Métal lourd, Taux, Sérum, Sang, Epidémiologie, Suède, Europe, Poisson comestible, Régime alimentaire, Amalgame, Dent, Mercure(méthyl)
Mots-clés Pascal anglais : Mercury, Heavy metal, Rate, Serum, Blood, Epidemiology, Sweden, Europe, Edible fish, Diet, Amalgams, Tooth
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0315619
Code Inist : 002B03L05. Création : 27/11/1998.