To determine the incidence rate (IR) and subtypes of dementia in southern Taiwan.
From a cohort of 2,915 community inhabitants aged 65 years and over, 2,507 and 2,175 subjects participated in the first-and second-year follow-up surveys, respectively.
A two-phase study used the Mini-Mental State Examination in phase I and the Consortium to Establish a Registry of Alzheimer's Disease (CERAD) neuropsychological battery and the neurobehavioral examination in phase II.
We applied International Classification of Diseases (ICD) - 10NA criteria for dementia, National Institute of Neurological and Communication Disorders and Stroke-Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) guidelines for Alzheimer's disease (AD), and National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche et l'Enseignement en Neurosciences (NINDS-AIREN) criteria for vascular dementia (VaD).
The annual IR for total dementia was 1.28%, which increased with age from 0.77% for 65-to 74-year-olds to 6.19% for persons aged 85 years or older.
AD (25 cases, 41.7%, IR=0.54%) was the most common cause of dementia, followed by VaD (19 cases, 31.7%, IR=0.41%) and mixed dementia (9 cases, 15.0%). After adjusting for sex, increasing age was significantly associated with total dementia and AD (p<0.01).
Illiteracy was associated with a marginally increased risk for total dementia (aRR=1.59, p<0. (...)
Mots-clés Pascal : Démence, Soustype, Taiwan, Asie, Sud, Facteur sociodémographique, Psychométrie, Mortalité, Prévalence, Incidence, Epidémiologie, Facteur risque, Vieillard, Homme, Système nerveux pathologie, Trouble neurologique, Trouble cognition
Mots-clés Pascal anglais : Dementia, Subtype, Taiwan, Asia, South, Sociodemographic factor, Psychometrics, Mortality, Prevalence, Incidence, Epidemiology, Risk factor, Elderly, Human, Nervous system diseases, Neurological disorder, Cognitive disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0312197
Code Inist : 002B17A01. Création : 27/11/1998.