The incidence and severity of rheumatoid arthritis. Results from a county register in Oslo, Norway.
To examine the incidence of rheumatoid arthritis (RA) in the community of Oslo, Norway ; and to link the incidence to measures of disease severity.
A register for RA in the county of Oslo was validated to be 85% complete for patients between 20 and 79 years of age.
The incidence of RA was calculated from this register for patients with disease onset 1988-1993 (n=550).
Data on health related quality of life [Modified Health Assessment Questionnaire (MHAQ).
Arthritis Impact Measurement Scale 2 (AIMS2), pain. fatigue] were obtained from a postal survey (response rate 73%). Results.
The overall annual incidence of RA over a 6 year period was 25.7/100,000 (females 36.7, males 13.8).
The incidence increased with age, from 7.8 in the age group 20-29 to 61.0 between 70 and 79 years.
After 5 year followup a clinically important effect on physical function (MHAQ>1.5) was seen in 38% of the patients, on social functioning (AIMS2 social>4) in 50%, on mental distress (AIMS2 affect>4) in 27%, on pain (VAS>40 mm) in 35%, and on fatigue (VAS>40 mm) in 41%. Conclusion.
The incidence of RA was 25.7/100,000 in the population of Oslo.
After 5 years, 40-50% had clinically important changes in health status.
The annual disease incidence with clinically important effect on physical function after 5 years was 10/100,000 individuals at risk.
Mots-clés Pascal : Polyarthrite rhumatoïde, Symptomatologie, Indice gravité, Epidémiologie, Incidence, Registre, Questionnaire, Norvège, Europe, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune, Milieu urbain
Mots-clés Pascal anglais : Rheumatoid arthritis, Symptomatology, Severity score, Epidemiology, Incidence, Register, Questionnaire, Norway, Europe, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease, Urban environment
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0311790
Code Inist : 002B15D. Création : 27/11/1998.