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  1. The incidence and severity of rheumatoid arthritis. Results from a county register in Oslo, Norway.

    Article - En anglais


    To examine the incidence of rheumatoid arthritis (RA) in the community of Oslo, Norway ; and to link the incidence to measures of disease severity.


    A register for RA in the county of Oslo was validated to be 85% complete for patients between 20 and 79 years of age.

    The incidence of RA was calculated from this register for patients with disease onset 1988-1993 (n=550).

    Data on health related quality of life [Modified Health Assessment Questionnaire (MHAQ).

    Arthritis Impact Measurement Scale 2 (AIMS2), pain. fatigue] were obtained from a postal survey (response rate 73%). Results.

    The overall annual incidence of RA over a 6 year period was 25.7/100,000 (females 36.7, males 13.8).

    The incidence increased with age, from 7.8 in the age group 20-29 to 61.0 between 70 and 79 years.

    After 5 year followup a clinically important effect on physical function (MHAQ>1.5) was seen in 38% of the patients, on social functioning (AIMS2 social>4) in 50%, on mental distress (AIMS2 affect>4) in 27%, on pain (VAS>40 mm) in 35%, and on fatigue (VAS>40 mm) in 41%. Conclusion.

    The incidence of RA was 25.7/100,000 in the population of Oslo.

    After 5 years, 40-50% had clinically important changes in health status.

    The annual disease incidence with clinically important effect on physical function after 5 years was 10/100,000 individuals at risk.

    Mots-clés Pascal : Polyarthrite rhumatoïde, Symptomatologie, Indice gravité, Epidémiologie, Incidence, Registre, Questionnaire, Norvège, Europe, Homme, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune, Milieu urbain

    Mots-clés Pascal anglais : Rheumatoid arthritis, Symptomatology, Severity score, Epidemiology, Incidence, Register, Questionnaire, Norway, Europe, Human, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease, Urban environment

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0311790

    Code Inist : 002B15D. Création : 27/11/1998.