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  1. Alcohol and morbidity in the Lung Health study.

    Article - En anglais

    Objective 

    There is a well documented J-shaped relationship between alcohol consumption and mortality that is not fully understood.

    Differences between studies, particularly in the use of cigarette smoking as a covariate, may partially explain inconsistencies in findings.

    This study sought to clarify the nature of this alcohol-smoking-mortality relationship.

    Method 

    The Lung Health Study enrolled 5,887 (3,702 male ; 95% white) cigarette smokers with airways obstruction, aged 35 to 60.

    Measures of smoking, drinking and body mass index were available annually over the 5-year duration of the study, and pattern of alcohol use and diastolic blood pressure were assessed at baseline.

    Heavy drinkers were excluded from the sample.

    Documented evidence of hospitalizations was used in establishing morbidity.

    Proportional hazards regression was used for analysis.

    Results 

    A significant protective effect of moderate drinking was found among men, but not women.

    There was also no apparent interaction between smoking status and drinks per week (both time dependent) in these data on morbidity and mortality.

    A baseline pattern of drinking eight or more drinks per occasion, but less than once a month, among men was associated with fewer hospitalizations and deaths.

    Conclusions 

    This study confirmed the general relationships between use of alcohol and illness or death, but with a few unexpected results. (...)

    Mots-clés Pascal : Consommation, Boisson alcoolisée, Tabac, Tabagisme, Complication, Mortalité, Epidémiologie, Facteur risque, Etude longitudinale, Santé mentale, Homme

    Mots-clés Pascal anglais : Consumption, Alcoholic beverage, Tobacco, Tobacco smoking, Complication, Mortality, Epidemiology, Risk factor, Follow up study, Mental health, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0309416

    Code Inist : 002B03F. Création : 27/11/1998.