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  1. Descriptive epidemiology of Creutzfeldt-Jakob disease in six European countries, 1993-1995.

    Article - En anglais

    After the occurrence of bovine spongiform encephalopathy (BSE), there has been concern that transmission of BSE to the human population might result in a change in the epidemiological characteristics of Creutzfeldt-Jakob disease (CJD).

    A collaborative study of CJD in the European Union was performed from 1993 to 1995, to compare data from national registries for CJD in France, Germany, Italy, The Netherlands, Slovakia, and the United Kingdom.

    Five hundred seventy-five patients with definite or probable CJD died in the study period with an overall annual mortality rate of 0.71 cases per million.

    The incidence rates for CJD were similar in all participating countries despite variations in postmortem rates, and age-specific incidence rates were also relatively consistent, with the exception of an increased incidence of CJD in patients younger than 39 years of age in the United Kingdom.

    In relation to etiological subtypes of CJD, 87% of cases were sporadic, 8% genetic, and 5% iatrogenic.

    Genetic forms of CJD comprised 80% of all cases in Slovakia, and iatrogenic forms of CJD occurred most frequently in France and the United Kingdom.

    The statistical data reported here do not provide evidence of a causal link between BSE and CJD in Europe as a whole. (...)

    Mots-clés Pascal : Encéphalopathie spongiforme Creutzfeldt Jakob, Infection, Epidémiologie, 1993, 1994, 1995, France, Europe, Allemagne, Italie, Pays Bas, Slovaquie, Royaume Uni, Homme, Prion, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative

    Mots-clés Pascal anglais : Creutzfeldt Jakob disease, Infection, Epidemiology, 1993, 1994, 1995, France, Europe, Germany, Italy, Netherlands, Slovakia, United Kingdom, Human, Prion, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0304760

    Code Inist : 002B17G. Création : 27/11/1998.