We compared the clinical outcome of acute diarrhea in 96 malnourished boys (aged 4 to 47 months) receiving full-strength milk compared with yogurt offered as part of a mixed diet.
All had weight for height less than or equal to 80% of the National Centre for Health Statistics median.
They were randomly assigned to receive milk formula (MF ; 67 cal/100 ml) or yogurt formula (YF ; prepared from the same milk formula) at the rate of 120 ml/kg body weight in seven divided feedings.
Stool-reducing substances (>1%) were detected more frequently in the MF group, and the differences were significant for day 3 of the study (p=0.04).
However, the geometric mean (95% confidence interval) of the total stool weights (gm/kg) during 0 to 72 hours (MF 128.8 [103,161.4] ; YF 110.9 [87,142.2]) was comparable (p=0.37) as was the median (range) duration of diarrhea (hours) (MF 45 [4,183] ; YF 52 [7,173] p=0.94).
The treatment failure rates in the MF (8.2%) and YF (6.3%) groups were also similar (p=0.67).
The children consuming milk had higher median percent weight gain at the end of 72 hours of the study (p=0.04) and at recovery (p=0.02).
Routine substitution of yogurt as small frequent feedings as an addition for semisolid food to malnourished children with acute diarrhea does not achieve any significant clinical benefit versus milk.
Mots-clés Pascal : Diarrhée, Corrélation, Malnutrition, Lait, Etude comparative, Yaourt, Randomisation, Enfant, Homme, Inde, Asie, Efficacité traitement, Appareil digestif pathologie, Intestin pathologie, Nutrition, Organisation santé
Mots-clés Pascal anglais : Diarrhea, Correlation, Malnutrition, Milk, Comparative study, Yogurt, Randomization, Child, Human, India, Asia, Treatment efficiency, Digestive diseases, Intestinal disease, Nutrition, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0302187
Code Inist : 002B02N. Création : 27/11/1998.