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  1. Clinical outcome in relation to care in centres specialising in cystic fibrosis : cross sectional study. Commentary.

    Article - En anglais


    To assess the effect on clinical outcome of managing paediatric and adult patients with cystic fibrosis at specialised cystic fibrosis centres.


    Cross sectional study.


    Two adult cystic fibrosis centres in the United Kingdom.


    Patients from an adult cystic fibrosis centre in Manchester were subdivided into those who had received continuous care from paediatric and adult cystic fibrosis centres (group A), and those who had received paediatric care in a centre not specialising in cystic fibrosis followed by adult care in a cystic fibrosis centre (group B).

    Group C were referrals to the new adult cystic fibrosis centre in Cambridge who had received neither paediatric nor adult centre care for their cystic fibrosis.

    Main outcome measures 

    Body mass index (weight (kg)/height (m2)), lung function (forced expiratory volume in one second (FEV1 percentage of predicted)), the Northern chest x ray film score, and age at colonisation with Pseudomonas aeruginosa.


    A prominent stepwise increase in body mass index was associated with increasing amounts of care at a cystic fibrosis centre ; 18.13,20.2, and 21.3 for groups C, B, and A respectively (P<0.001).

    Improved nutritional status was correlated with a higher FEV, and better (lower) chest x ray film scores ; r=0.52 and - 0.45 respectively (P<0.001 for both). (...)

    Mots-clés Pascal : Mucoviscidose, Etude transversale, Corrélation, Soin intégré, Stratégie, Facteur efficacité, Pédiatrie, Adulte, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe, Appareil respiratoire pathologie, Appareil digestif pathologie, Pancréas pathologie, Maladie héréditaire, Métabolisme pathologie, Organisation santé

    Mots-clés Pascal anglais : Cystic fibrosis, Cross sectional study, Correlation, Managed care, Strategy, Effectiveness factor, Pediatrics, Adult, Human, England, Great Britain, United Kingdom, Europe, Respiratory disease, Digestive diseases, Pancreatic disease, Genetic disease, Metabolic diseases, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0301989

    Code Inist : 002B13B03. Création : 27/11/1998.