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  1. Epidemiology, appropriateness, and cost of vancomycin use.

    Article, Communication - En anglais

    Emerging Resistance with Gram-Positive Aerobic Infections : Where Do We Go Here. Symposium. New Orleans, USA, 1996/09/14.

    Pharmaceutical costs, which approach $40 billion annually, account for about 8% of health care costs.

    Prescription drugs represent 5% to 20% of the total hospital budget, and antimicrobials account for 20% to 50% of hospital pharmaceutical costs.

    At one university hospital, the percentage of patients receiving antimicrobials increased from 31.8% in 1988 to 53.1% in 1994.

    Receipt of vancomycin has been associated with the emergence of resistant enterococci and has resulted in Centers for Disease Control and Prevention (CDC) recommendations for its use.

    Studies show that vancomycin use is increasing, that dosing is often inappropriate, that certain populations (such as oncology, neurosurgery, and cardiovascular surgery patients) are more likely to receive vancomycin, and that often use is not consistent with CDC recommendations.

    Few studies have assessed the cost of vancomycin use ; those that have show that it is costly.

    Further studies of vancomycin use are needed, so that use can be improved through focused educational programs.

    Mots-clés Pascal : Augmentation, Prescription médicale, Homme, Vancomycine, Complication, Résistance traitement, Epidémiologie, Coût, Géorgie, Etats Unis, Amérique du Nord, Amérique, Glycopeptide, Polypeptide, Economie santé

    Mots-clés Pascal anglais : Increase, Medical prescription, Human, Vancomycin, Complication, Negative therapeutic reaction, Epidemiology, Costs, Georgia, United States, North America, America, Glycopeptide, Polypeptide, Health economy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0297443

    Code Inist : 002B02S02. Création : 27/11/1998.