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  1. Changing trends in esophageal cancer : A 15-year experience in a single center.

    Article - En anglais

    Objective 

    Esophageal adenocarcinoma is increasing in white men.

    We sought to identify trends in esophageal cancer in different patient groups in our region.

    Methods 

    We reviewed the records of all patients with esophageal cancer seen at two hospitals in Columbia, SC between 1981 and 1995.

    Patients were divided into three cohorts (1981-1985,1986-1990, and 1991-1995).

    Demographic data, histological type, tumor stage, grade, and survival were recorded.

    Results 

    Histology was available in 371 of 386 patients (cohort 1,113 patients ; cohort 2,144 ; and cohort 3,114).

    Adenocarcinoma accounted for 24%, 27%, and 49% of esophageal cancer in white men in cohorts 1,2, and 3, respectively=0.03).

    Corresponding figures for African-Americans were 10%, 7%, and 3% (p=0.22).

    Women comprised 8%, 14%, and 22% of patients with squamous carcinoma in the three cohorts (p=0.03).

    Median survival for esophageal cancer was 6.0,6.8, and 10.4 mo in cohorts 1,2, and 3 (p=0.0002).

    Conclusion 

    Adenocarcinoma is increasing in whites.

    Squamous carcinoma remains the predominant type in this region, seen mainly in African-Americans.

    Esophageal squamous carcinoma is increasing in women.

    The mean age at diagnosis of squamous carcinoma has decreased in whites.

    There is a trend toward improved survival in patients with esophageal cancer.

    Mots-clés Pascal : Carcinome, Oesophage, Evolution, Epidémiologie, Incidence, Type histologique, Stade clinique, Grade histologique, Survie, Etude cohorte, Homme, Caroline du Sud, Etats Unis, Amérique du Nord, Amérique, Tumeur maligne, Appareil digestif pathologie, Oesophage pathologie, Histopathologie

    Mots-clés Pascal anglais : Carcinoma, Esophagus, Evolution, Epidemiology, Incidence, Histological type, Clinical stage, Histological grading, Survival, Cohort study, Human, South Carolina, United States, North America, America, Malignant tumor, Digestive diseases, Esophageal disease, Histopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0295693

    Code Inist : 002B13A01. Création : 27/11/1998.