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  1. Multi-resistant Pseudomonas aeruginosa outbreak associated with contaminated tap water in a neurosurgery intensive care unit.

    Article - En anglais

    From July 1995 to November 1996, multi-resistant Pseudomonas aeruginosa 011 was isolated from 36 patients admitted to a neurosurgery intensive care unit.

    The strain, as resistant to ticarcillin, ceftazidime, imipenem, gentamicin and ciprofloxacin, and susceptible to amikacin.

    Nine patients were colonized only ; the remaining 27 patients had at least one infected site (17 urinary infections, 10 pneumonias and four with sinusitis).

    P. aeruginosa 011 with the same resistance pattern was isolated from tap water.

    The strain was also cultured from enteral nutrition solutions given to two infected patients.

    DNA macrorestriction analysis with Xbal established the similarity of the isolates from patients, tap water and solutions.

    The outbreak was controlled after reinforcement of isolation procedures for infected patients, changing the mode of enteral nutrition and replacement of all sinks in the unit.

    The sinks were presumably the main source of P. aeruginosa during this outbreak, via the hands of the nursing staff or nutrition solutions contaminated with tap water.

    Mots-clés Pascal : Pseudomonas aeruginosa, Pseudomonadaceae, Pseudomonadales, Bactérie, Unité soin intensif, Chirurgie, Neurologie, Résistance traitement, Antibactérien, Antibiotique, Chimiothérapie, Eau distribution, Contamination, Epidémiologie, Infection nosocomiale, Epidémie, Homme, France, Europe, Service hospitalier, Soin intensif

    Mots-clés Pascal anglais : Pseudomonas aeruginosa, Pseudomonadaceae, Pseudomonadales, Bacteria, Intensive care unit, Surgery, Neurology, Negative therapeutic reaction, Antibacterial agent, Antibiotic, Chemotherapy, Tap water, Contamination, Epidemiology, Nosocomial infection, Epidemic, Human, France, Europe, Hospital ward, Intensive care

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0290793

    Code Inist : 002B05B02P. Création : 27/11/1998.